Are People With MS at Higher Risk for COVID-19?

Julie Fiol, RN, the director of MS information and resources for the National Multiple Sclerosis Society (NMSS), tells Verywell that some of the indirect effects of MS and its treatment can increase a person’s risk for COVID-19.

Although MS itself isn’t a risk factor for COVID-19, Fiol says that “certain factors associated with” it are. These include obesity, severe disability, heart conditions, and lung conditions.

Another consideration is disease-modifying therapy (DMT) adherence. DMTs are the prescription medications, injections, and infusions that can significantly reduce the severity and frequency of relapses, but also dampen the immune system. This could increase COVID-19 risk.

Which MS Patients Should Be Prioritized for Vaccination?

Considering these risks, NMSS is advocating for certain subgroups of people with MS to be prioritized for the COVID-19 vaccine.

The disease remains a medical mystery in many respects, but it is known to affect almost three times as many women as men.

Fiol says that some people with MS are more vulnerable to infection, illness, and death than others. Subgroups at higher risk include:

Men with MSPeople with progressive MSBlack and possibly South Asian people with MSPeople over the age of 60 with MSPeople with serious mobility issues

“Vaccination against COVID-19 is critical for public safety and, especially, the safety of the most vulnerable among us,” Fiol says. “The authorization of safe and effective vaccines for COVID-19 brings us one step closer to eliminating this pandemic.”

Are COVID-19 Vaccines Safe for People With MS?

NMSS has deemed the Moderna and Pfizer-BioNTech vaccines safe for use in people with MS. The organization will make a decision about the Janssen/Johnson & Johnson vaccine soon.

“We hope to have guidance on the J&J vaccine available to people with MS soon, but it’s too early for me to predict a date,” Fiol says, adding that members of its Vaccine Advisory Group met on March 4 to review relevant CDC guidelines and FDA data.

In the meantime, if you have MS, Fiol recommends talking to your provider about the particulars of your medical history—including previous vaccination experiences before getting a COVID-19 shot.

MS Treatment and Vaccine Effectiveness

If you are receiving disease-modifying therapy (DMT), be sure to ask your doctor if your treatment will interfere with the vaccine’s effectiveness.

Will getting the vaccine trigger an MS relapse?Should I expect to have the same side effects as someone who does not have MS?Will I need to continue to take safety precautions such as masking and socially distancing after vaccination?

While most DMTs will not affect your body’s response to a vaccine—COVID-19 or otherwise—there are a few that Fiol says “may make the vaccine less effective” by dampening your body’s immune response.

If you can, try to coordinate your vaccination and DMT treatment to be two, four, or more weeks apart. If that’s not possible, ask your doctor about the best way to manage both your treatment and vaccine schedule.

“Given the potential serious health consequences of COVID-19 disease and the worldwide shortage of vaccines, getting the vaccine when it becomes available may be more important than optimally timing the vaccine with [your] DMT,” Fiol says. “People with MS should work with their healthcare provider to determine the best time for them to get vaccinated.”

The information in this article is current as of the date listed, which means newer information may be available when you read this. For the most recent updates on COVID-19, visit our coronavirus news page.

National Multiple Sclerosis Society. Multiple sclerosis & coronavirus.